IP Requirements:

• CHOA IP

Experience Requirements:

• Mixed Skill Set
  

Endovascular therapy has revolutionized the treatment of thoracic aortic aneurysms and dissections over the past 25 years.  In a similar fashion transcatheter heart valve therapy has revolutionized the treatment of aortic valve disease over the past 15 years.  However the last frontier which has remained challenging for transcatheter therapies is the aortic root due to its complex structure and anatomy.

The aortic root complex begins at the base of the heart at the aortic valve annulus.  It extends up to the sinotubular junction where the ascending aorta begins.  Within the aortic valve complex is the aortic valve , and the origins of the left and right coronary artery ostia.  Therefore, transcatheter treatment of this location in the aorta would require valve replacement while maintaining patency of the coronary arteries.  Currently there is an unmet need due to a lack of technology to treat this area with transcatheter devices.  Patients who could potentially benefit from such a transcatheter/endovascular valved-conduit would include patients with aortic dissection, aortic root aneurysms, or aortic valve disease with an aortic valve annulus that is too large for currently available transcatheter heart valve devices.